A Flip Turn for Membrane Protein Insertion

نویسندگان

  • Sichen Shao
  • Ramanujan S. Hegde
چکیده

The transmembrane domains in a membrane protein must be recognized and correctly oriented before their insertion into the lipid bilayer. Devaraneni et al. (2011) generate snapshots at different stages of membrane protein biogenesis, revealing a dynamic set of steps that imply an unexpectedly flexible membrane insertion machinery.

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عنوان ژورنال:
  • Cell

دوره 146  شماره 

صفحات  -

تاریخ انتشار 2011